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Medicina (Kaunas) 2004; 40 (8): 768-770

Bee products for treatment of diseases of mouth and upper respiratory tract

Antanas Gendrolis, Liudas Ivanauskas1, Audronis Lukošius2, Valdemaras Brusokas2

Department of Drug Technology and Pharmaceutical Management, 1Department of Analytical and Toxicological Chemistry, 2Department of Pharmaceutical Chemistry and Pharmacognosy, Kaunas University of Medicine, Lithuania

Key words: honey, propolis, ethanol, spray.

Summary. Production of spray (from bee products), which is used for mouth and upper respiratory tract disease treatment and prevention, is described in this article. The optimal technology of spray is prepared, and concentration of ethanol as extragent 70% and 15% of honey is determined. The preparation is called propomel. Methods of analysis were applied, investigations of stability were performed, time of suitableness was determined, as well as the normative and technical documentation was prepared.

Correspondence to L. Ivanauskas, Department of Analytical and Toxicological Chemistry, Kaunas University of Medicine, A. Mickevičiaus 9, 44307 Kaunas, Lithuania. E-mail: liudasi@takas.lt

Received 23 March 2004, accepted 10 June 2004